I made a Ginormous discovery -
When I just use only my main Titan Xp on the Mobo, I get NO issues with any of things I have been yapping about related to crashing-
1) Saving EXR, 16 bit PNG
2) GPUs going orange-warning when changing AI-sampling modes
3) not being able to use Render passes with up-sampling
BUT - as soon as I enter in either my 1 Titan X Pascal, which is also on Mobo, or my 6 external Titan X Pascals connected on PCI 1x USB 3.0 risers, I get the issues...
In fact, with just 1 Titan X Pascal, either on Mobo or external, things fail. For example, with render passes when using up-sampling GPU gets the red warning that it failed.
Almost as if XB2 can't work right with Titan X Pascal.
Now, XB1 had no Titan X Pascal issues, so this is very interesting, weird, and most importantly...
FUN 
Win 10 Pro 64, Xeon E5-2687W v2 (8x 3.40GHz), G.Skill 64 GB DDR3-2400, ASRock X79 Extreme 11
Mobo: 1 Titan RTX, 1 Titan Xp
External: 6 Titan X Pascal, 2 GTX Titan X
Plugs: Enterprise