I use max 4 octane on a daily basis.
So since I and any other users do not report the issue.
Your problem seems to be occurring in your current setup only.
I sadly have no suggestions than re installing max, Not sure if it work though.
if you own standalone along with octane for max. test if it works with standalone.
If you only have max plugin. make sure your license might need to have both standalone and max activated on same machine.
Maybe re-install a lower version of max ( say if you do your main work on max 2015, re-install max2014 or 2016 )
That way you wont loose any of the settings or scripts in your main max version
See if you have the same problem with those.
İf they have the same problem after you install. Than the problem might be with the nvidia drivers.
Uninstall all of the nvidia drivers.
Restart with no nvidia drivers installed. And then install a previous version of the nvidia driver. (the one before latest driver)
Lastly One of your gpu's might be failing. remove all but one cards and test again.
You can just solve it by eliminating suspects one by one
Edit: Then pay me