At one moment, Gainward produced GTX280 with 2GB of VRAM, it seems that it is very difficult to find them now. It was interesting for big scenes and I was thinking of purchasing two of them before we got informations about GTX 480 release, but if I remember well the images seen, Gainward GTX 280 had big heat pipes on a side, and it is a thing to take in account for Cubix box owners, I think ?
Probably not really a problem for most desktop computers with big towers but in Cubix Xpander there is very few room in the box on top of the graphic cards, and I may be wrong, but I am almost sure that Gainward cards don't fit in the Cubix box because of their vertical dimension.
Just a precision for people who would make this choice before purchasing the Cubix or would have not seen photos of the Gainward GTX 280.
EDIT :

Hmm, I got a doubt, and so I have given a look at the site of a hardware seller, and they don't sell GTX 280 any more, so I have only seen Gainward GTX 285 1GB with big pipes. I can't verify if GTX 280 had big pipes too. Anyway, be careful if you want to purchase one.
French Blender user - CPU : intel Quad QX9650 at 3GHz - 8GB of RAM - Windows 7 Pro 64 bits. Display GPU : GeForce GTX 480 (2 Samsung 2443BW-1920x1600 monitors). External GPUs : two EVGA GTX 580 3GB in a Cubix GPU-Xpander Pro 2. NVidia Driver : 368.22.