I have this MOBO of times they had either SLI or Crossfire, not both. And the M4A785TD-V is one of that went crossfire only.

I know Octane does not use SLI and I'm not hoping for it, but I'm concerned:
1. Will the MOBO be able to run 2 nvidia cards independently so I can use both with Octane?
2. Given the attached photo of the system in particular, should I worry about the PSU proximity to 2nd GPU slot? Is the case layout a yellow or red flag?
3. Will the "display card" always be the one where the monitor is plugged in? Or could I somehow have the GTX 780 running games, and the GTX 560ti be the display card when running octane in maya?
Also, I'm tempted towards the 780 instead of the 580 - for games too, true - but also because of temperature-noise. I've read that kepler is much more candid in that front (also there's a good sale and store warranty). Local temperatures can reach 30ºC. Any further considerations are also welcomed.