Another update. I dropped down to 14000 x 12250 and am able to toggle post processing on and off without issue, but cannot save out an exr, or even a png w/ post enabled.
According to the attached image below, there is plenty of video and system RAM left, even if Octane is not fully optimizing RAM resources. No other apps are running.
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Win7 | Geforce TitanX w/ 12Gb | Geforce GTX-560 w/ 2Gb | 6-Core 3.5GHz | 32Gb | Cinema4D w RipTide Importer and OctaneExporter Plugs.