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Is this possible? I had tried fluid and cloth ... those are no problem, as it only calculates a mesh fram by frame, which you can then render as animation, works without problems with Octane. But Fire is weird and uses internal "volume material" definition it seems and can only work with blender internal engines? At least I didn't see how you can just calculate something there and let it render by Octane. I'm trying to create a realistic explosion.

No that isn't possible. The most you can get is a fairly cartoonish smoke render. The problem is that you have to convert your volumetric smoke/fire (voxels) down to the hull (mesh) and from there you can add an fog material. You will lose every fluid and color information inside the "hull". Here's a test I've done (colored fog material on a smoke hull):