Can confirm that with:
nVidia 419.17
Octane Standalone 4.02
Octane for Cinema4D 4.02.1 - R3
2x 1080Ti
Octane lets the Cinema 4D application crash.
Reverting back now
EDIT:
The following configuration is working:
nVidia - 417.71
Octane Standalone - 4.01.1
Octane for Cinema4D - 4.01.1 - R2
EDIT2:
DDU was not used, the bugged driver was normally removed one by one, then reboot, then 417.71 was installed with "Custom Installation" and then "Perform Clean Install" box checked.