Funny thing, from some quick testing on a heavy scene I was working with the Multi-Core option ON it all really slowed down shader generation / refreshes. Any change to a shader in a heavy scene caused a 1 second UI freeze throughout C4D. My CPUs are 2x 2696v3 Xeons.
All that said, that was in the 2019 version, haven't tested it in the latest 2020 which by the way looks like a really awesome update to me!
Can't wait to see the multi-threading in action, such an awesome surprise!